(l-r) Drs. Marchese, Baboolal, Lussier, Rivera-Santiago, Krinsley and Khodorskiy presenting at the 2011 SCCM Critical Care Congress in San Diego, California.

Research Opportunities

Clinical Research Involving IM Residents in the Stamford Hospital ICU - 2010

Active projects

• Glycemic control in critically ill patients treated with parenteral steroids** -Bethany Lussier

• Relationship of elevations of Troponin to mortality in medical ICU patients** -Dmitriy Khodorskiy and Michael Marchese

• Association of mortality with even modest degrees of hypoglycemia in medical ICU patients**-Bethany Lussier

• The relationship between hyperglycemia occurring during ICU admission and subsequent development of diabetes mellitus -Victor Rivera-Santiago

• Medical readmissions to the ICU: risk factors and outcomes* -Bethany Lussier

• Randomized evaluation of H2 blocker vs. PPI in ventilated patients# -Susan Mucha (recent graduate)

• Pre-admission functional status of patients admitted to the medical intensive care unit: independent effect on mortality and length of stay^ -Matthew Porac
  

• While we wait for the future: intensive glycemic management using combinations of subcutaneous and intravenous insulin in the critically ill^ -Suraj Jacob
  

• Glycemic control in critically ill patients: impact of age^ -Jason Lawrence ( recent graduate)
  

• Glycemic control in critically ill patients: impact of gender^ -Susan Mucha (recent graduate)
  

• Glycemic control in critically ill patients: impact of race^ -Mohammed Shams
  

• Temporal trends in red blood cell transfusions for patients admitted to the medical ICU^ -Phalgun Prativadi
  
  Note:
  * Abstract presented at the 2009 Society of Critical Care Medicine international congress; manuscript under preparation
  # Data collection ongoing
  ^ Abstract presented at the 2010 Society of Critical Care Medicine international congress; manuscript under preparation
  **Abstract to be submitted for presentation at the 2011 Society of Critical Care Medicine international congress

Published Manuscript

Krinsley JS, Grover A. Severe hypoglycemia in critically ill patients: risk factors and outcomes. Crit Care Med. 2007; 35: 2262-2267.

Published Abstracts

Intintoli A, Sachs P, Krinsley JS. Outcome of patients admitted to the intensive care unit with gastrointestinal hemorrhage complicated by myocardial infarction. Crit Care Med. 2003; 31:A259.
 
Bennet S, Krinsley JS. Outcome of critically ill patients with congestive heart failure who "rule in" for myocardial infarction. Crit Care Med. 2004; 32:A162.

Krinsley JS, Ahmed, M. Incomes and outcomes in critically ill patients. Crit Care Med. 2004; 32:A270.

Kedem R, Krinsley JS. Does having a religious affiliation affect the outcome of ICU patients? Crit Care Med. 2004; 32:A260.

Krinsley JS, Dachinger E. Critically ill cardiac patients: the impact of diabetic status and glycemic variability. Crit Care Med. 2008; 36:A393.

Krinsley JS, Drummond J. Readmission to the medical intensive care unit: risk factors and outcomes. Crit Care Med. 2008; 36:A325.
 
Krinsley JS, Lawrence J. Glycemic control in critically ill patients: impact of age. Crit Care Med. 2009; 37:A713.

Krinsley JS, Mucha S. Glycemic control in critically ill patients: impact of gender. Crit Care Med. 2009; 37:A688.

Krinsley JS, Shams M. Glycemic control in critically ill patients: impact of race. Crit Care Med. 2009; 37:A699.

Krinsley JS, Porac M. Pre-admission functional status of patients admitted to the medical intensive care unit: independent effect on mortality and length of stay. Crit Care Med. 2009; 37:A594.

Krinsley JS, Prativadi P. Temporal trends in red blood cell transfusions for patients admitted to the medical ICU. Crit Care Med. 2009; 37:A700.

Krinsley JS, Jacob S. While we wait for the future: intensive glycemic management using combinations of subcutaneous and intravenous insulin in the critically ill. Crit Care Med. 2009; 37:A668.

Third year residents are required and residents in their first and second year encouraged to present either a poster or oral presentation at the Connecticut Chapter of the American College of Physicians' Scientific Session. With the full support and guidance of an inspiring and supportive teaching faculty, the following presentations were made in 2010.
 
"Severe Warm Agglutinin Autoimmune Hemolytic Anemia (AIHA)," by Brent Baboolal, M.D.

"While We Wait for the Future:  Intensive Glycemic Management Using Combinations of Subcutaneous and Intravenous Insulin in the Critically Ill," by Suraj Jacob, M.D. and James Krinsley, M.D.

"Pre-Admission Functional Status and Effect on Mortality and Intensive Care Unit Length of Stay," by Matthew Porac, M.D. and James Krinsley, M.D.
 
"Temporal Trends in Red Blood Cell Transfusion in the Medical ICU," by Phalgun Prativadi, M.D. and James Krinsley, M.D.

"Sarcoidosis as a Mimic of Lymphoma Recurrence," by Arvind Sahota, M.D., Abid Iqbal, M.D. and Anne Angevine, M.D.
 
"Glycemic Control in Critically Ill Patients: Impact of Race," by Mohammed Shams, M.D. and James Krinsley, M.D.

"Extramedullary Hematopoiesis in the Lung, Presenting as Pulmonary Hypertension," by Abid Iqbal, M.D., Arvind Sahota, M.D. and Anne Angevine, M.D.

"A Fatal and Rare Association of Autoimmune Hemolytic Anemia and Primary Sclerosing Cholangitis," by Fouad Otaki, M.D., Robert Dettmer, M.D., Anne Angevine, M.D. and Kirsten Hohmann, M.D.

Two dedicated Medical Grand Rounds in the Spring of the academic year are always devoted to presentations by senior medical residents.